ACP-ASIM Information: Membership
Change of
Address Residency
Database CME
Career Resource
Center Where we stand
Discussion
Groups Annals
Committees
Computers/Medicine
IM
Bookmarks Medline
|

Missouri Resident Poster Competition 1999
Paul K. Crane
M.D.
Washington University
Bacillus cereus
food poisoning as a cause for sepsis: a case report
Bacillus cereus was
only recently recognized as a cause of human disease. It is a
ubiquitous gram-positive aerobic spore-forming rod which
causes six different clinical syndromes: local infections,
bacteremia and septicemia, central nervous system infections,
respiratory infections, endocarditis and pericarditis, and
food poisoning. We describe the first reported case of a
patient with Bacillus cereus food poisoning thought to
have led to bacteremia and septicemia.
The patient is a 53 year old woman with a history of
osteomyelitis of her right femoral head, leading to chronic
intravenous antibiotics through a Hickman line. She did well
until two nights prior to admission when she went with her
mother to Chinese food. Both women ate the fried rice. Both
women noted the onset of crampy diarrhea several hours later.
The diarrhea was self-limited in the mother. The patient noted
increasing malaise, fevers, chills, and weakness, and
presented to the emergency department.
There, she was found to be in moderate distress, febrile to
38.4, hypotensive to 90/58, and tachycardic at 110.
Respirations were normal. Exam was marked in the poor hygiene
around the patient’s Hickman line; dressings were changed in
the emergency department. The patient responded well to
intravenous fluids. On the second hospital day, multiple sets
of blood cultures grew a gram positive rod, which was
identified on the third hospital day as Bacillus cereus. The
patient responded well to antibiotics and was sent home. Three
months following the admission there were no long-term
sequelae.
Most cases of Bacillus cereus bacteremia have been
linked to immunocompromised states or to intravenous drug use.
No case of bacteremia had been described in patients who
developed food poisoning initially. As patients are
increasingly being cared for in outpatient settings with
indwelling lines, cases similar to this one may be expected.
Certainly hygiene of the line site is essential, and better
education of patients will be required to prevent the risk of
serious complications from sepsis.
|