Diagnosis of acute pulmonary embolism using pulmonary artery
catheter
A 48 year old male firefighter was admitted due to respiratory
failure following an
explosive fire accident and acute lung injury. He was intubated and
aggressively
treated for carbon monoxide inhalation. Radiological imaging was
negative for fractures.
DVT prophylaxis was initiated with heparin and pneumatic compression
stockings.
The patient improved over the next 3 days, although he remained
intubated for airway
protection.
On the third day of hospitalization, he decompensated with severe
hypoxia and hypotension
which remained resistant to oxygen, fluids and vasopressors.
Lab results: ABG – 7.37/46 pCO2/ 75 pO2/93% on 70% FIO2; Chest
X-Ray, EKG and cardiac enzymes were negative; CBC and chemistry
remained unchanged; Duplex scan of the lower extremities was
negative for DVT. Simultaneously, a PS catheter was floated and the
following
tracing was obtained.
Severe pulmonary hypertension with normal pulmonary capillary
wedge pressure was noted consistent with acute pulmonary embolism.
There was a 12-mm gradient of pressure between
distal and proximal PS suggestive of saddle embolus. Heparin
was initiated and the diagnosis confirmed by lung perfusion scan.
Transthoracic echocardiogram revealed a right atrial thrombus.
Patient was emergently treated with thrombolytics with successful
resolution of hypoxia and hypotension. The PA catheter tracing no
longer showed a gradient in the pulmonary artery. A
repeat echocardiogram showed resolution of the thrombus. Over
the next few days, the patient
was extubated and subsequently discharged home on long term
anticoagulation.